Nov. 7

Saturday, Nov. 7, 2015

  Hall A Room 2
09:00-09:20 Opening
Michio Kimura : Chair, TBC2015
Mihoko Okada : President, Japanese Association for Medical Informatics
09:20-10:00 Keynote 1. Michio Kimura moderator: Mihoko Okada
Japan's Available Large Clinical Databases
 - Reimbursement claim data, Specialist qualification registry, and HL7 based standardized storage
10:00-10:30 Keynote 2. Yu-Chuan (Jack) Li moderator: Michio Kimura
Mapping Long-term-use Drugs and Personal Cancer Risk
10:30-11:00 Coffee Break
  S1. Data Privacy S2. Clinical Informatics for Translation
moderator: Jack Li moderator: Hideto Yokoi
11:00-11:25 Privacy-Preserving Mechanisms for Transmission Disequilibrium Test in Genome-Wide Association Studies An innovative model for reducing medication errors in computerized physician order entry (CPOE) system
11:25-11:50 SECRET: Secure Edit-distance Computation over homomoRphic Encrypted daTa BEST: Next-Generation Biomedical Entity Search Tool for Knowledge Discovery from Biomedical Literature
11:50-12:15 Secure Multi-pArty Computation Grid LOgistic REgression (SMAC-GLORE) Establishing a program for a clinical informatics subspecialty in Korea and needs assessment survey in physicians.
12:15-13:20 Lunch Break
13:20-14:20 Keynote 3. Yves A. Lussier moderator: Naoki Nakashima
The personalome era:  precision therapy with dysregulated molecular networks
  S3. Cancer Bioinformatics S4. Multi-omic Applications
moderator: Indira Ghosh moderator: Luonan Chen
14:20-14:45 SFRP1 is a possible candidate for epigenetic therapy in non-small cell lung cancer Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of EWS KO mice
14:45-15:10 Unraveling synthetic lethal interactions for therapeutics of lung adenocarcinoma Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer’s disease
14:10-14:35 Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer Using knowledge-driven genomic interactions for multi-omics data analysis: meta-dimensional models for predicting clinical outcomes in ovarian carcinoma
15:35-16:00 Discovering gene expression signatures responding to tyrosine kinase inhibitor treatment in chronic myeloid leukemia Alternative Polyadenylation in Cardiac Development and Hypertrophy
16:00-16:30 Coffee Break
16:30-17:30 Keynote 4. Lucila Ohno-Macado moderator: Ken Imai
Developing a large clinical data research network: the patient-centered SCAlable National Network for Effectiveness Research (pSCANNER)
17:30-18:00 Break
18:00- Welcome Reception (Room 4)
*Poster session in Room1  

Nov. 8

Sunday, Nov. 8, 2015

  Hall A Room 2
  S5. Linking Phenotypes
moderator: Indira Ghosh
08:30-08:55 Keynote 5:Hiroshi Tanaka IVIG administration in Kawasaki disease patients causes major methylation alterations on the CpG markers of inflammatory immune associated genes
moderator: Takako Takai
Japan Association for Omics-based Medicine
Complex systems theory of cancer metastasis
08:55-09:20 Journal and Publication Panel
Lucila Ohno-Machado (JAMIA: Editor-in-Chief)
Maricel Kan (JBI: Editorial Board)
Jack Li (CMPB: Editor-in-Chief)
moderator:  Yves A. Lussier
Semantics based approach for analyzing disease-target associations
09:20-09:45 Inferring Crohn's disease association from exome sequences by integrating biological knowledge
09:45-10:10 Coffee Break
10:10-11:10 Keynote 6: Marylyn D. Ritchie moderator: Hideto Yokoi
Electronic health records and genomics - a dynamic duo for precision medicine
11:10-12:10 Keynote 7: Toru Hosoda moderator: Naoki Nakashima
Translational Perspectives of Cardiac Regenerative Medicine
12:10-13:00 Lunch [Intel Special Session]
Modular, Scalable Computing Platform for Precision Medicine
Ketan Paranjape                moderator: Tomohiro Sawa
  Highlight Research S6. New Technologies
moderator: Marylyn D. Ritchie moderator: Luonan Chen
13:00-13:25 Extraction of Pharmacokinetic Evidence of Drug–Drug Interactions from the Literature EyeSee; an Assistive Device for Blind Navigation with Multi-Sensory Aid
13:25-13:50 Diagnostic Role of Exome Sequencing in Immune Deficiency Disorders PATTERN: Pain Assessment for paTients who can’t TEll using Restricted Boltzmann machiNe
13:50-14:15 hiHMM: Bayesian non-parametric joint inference of chromatin state maps. Creative Activity Aid using Active Tremor Cancellation
14:15-14:25 Break
14:25-15:25 Keynote 8: Griffin Weber   moderator:Hideto Yokoi
Analyzing, Visualizing, and Facilitating Scientific Collaboration
  S7. Bionformatics Algorithms S8. GAWS and Post-GWAS  
moderator: Ken Imai moderator: Maricel Kan
15:25-15:50 Fast Comparison of Genomic and Meta-Genomic Reads with Alignment-Free Measures based on Quality Values Genome-wide association study identifies novel susceptibility genes associated with coronary artery aneurysm formation in Kawasaki Disease
15:50-16:15 Parametric analysis of RNA-seq expression data Integrative Regression Network for Genomic Association Study
16:15-16:40 Nearest Neighbor Imputation Algorithms: A Critical Evaluation. eMERGE Phenome-Wide Association Study (PheWAS) Identifies Clinical Associations and Pleiotropy for Stop-Gain Variants
16:40-17:00 Coffee Break
17:00-18:00 Keynote 9: Rae Woong Park moderator: Ken Imai
Clinical Outcome Modeling & Simulation using EMR Big Data
*Poster session in Room1  

Nov. 9

Monday, Nov. 9, 2015

  Hall A Room 2
Session Tohoku Scientific Session S9. Biomedical Big Data
    moderator:  Ju Han Kim
08:30-08:55 Tohoku Medical Megabank Organization
- Overview of Tohoku Medical Megabank Project
- Deep whole genome sequencing Japanese healthy population
- Strategy of Three-Generation Cohort Study and Community Based Cohort Study
- Integrated Database Systems for personal genomic and healthcare information in Tohoku area
DataRank: A Framework for Ranking Biomedical Datasets
08:55-09:20 Many larger worlds in a small world
09:20-09:45 CLASH: Complementary Linkage with Anchoring and Scoring for Heterogeneous BioMolecular and Clinical Data
09:45-10:10 Coffee Break
10:10-11:10 Keynote 10: Maricel G. Kann modelator: Luonan Chen
11:10-11:40 Excellent Paper Award
Excellent Poster Award
11:40-12:00 Closing
Tomohiro Sawa
Ju Han Kim